Table 1.
Summary data from all GWAS used in the present study
| Phenotype | Sample size, n | Ancestry (n) | SNPs, n | Source |
|---|---|---|---|---|
| Discovery samples | ||||
| All epilepsy | 15 212 cases, 29 677 controls | 86% European (38 752), 8% Asian (3406), 6% African (2731) | 4 880 492 | ILAE2 |
| Focal epilepsy | 9671 cases, 29 677 controls | 84% European (33 313), 9% Asian (3365), 7% African (2670) | 4 862 782 | ILAE2 |
| GGE | 3769 cases, 29 677 controls | 83% European (27 926), 9% Asian (2875), 8% African (2645) | 4 867 068 | ILAE2 |
| SCZ | 45 313 cases, 67 472 controls | European | 7 634 648 | Trubetskoy et al.19 |
| BIP | 39 027 cases, 367 378 controls | European | 9 028 988 | Mullins et al.18 |
| DEP | 121 198 cases, 246 363 controls | European | 15 807 881 | Howard et al.17 |
| ADHD | 19 099 cases, 34 194 controls | European | 8 094 094 | Demontis et al.15 |
| ASD | 18 381 cases, 27 969 controls | European | 9 112 386 | Grove et al.16 |
| Independent samples | ||||
| All epilepsy | 2466 cases, 175 788 controls | European | 15 746 420 | https://r5.finngen.fi |
| SCZ | 22 778 cases, 35 362 controls | East Asian | 10 694 910 | Lam et al.22 |
| BIP | 4501 cases, 192 220 controls | European | 15 746 437 | https://r5.finngen.fi |
| DEP | 170 756 cases, 329 443 controls | European | 15 746 508 | https://r5.finngen.fi |
| ADHD | 4224 cases, 203 345 controls | European | 6 981 749 | MoBa; Magnus et al.43,44 |
| ASD | 925 cases, 206 644 controls | European | 6 981 749 | MoBa; Magnus et al.43,44 |
BIP = bipolar disorder; DEP = depression; SCZ = schizophrenia; ILAE = International League Against Epilepsy; MoBa = Norwegian Mother, Father and Child Cohort Study.