Table 2.

Univariate MiXeR estimates for the epilepsies and psychiatric disorders

Phenotype	ADHD	ASD	BIP	DEP	SCZ	EP	FEP	GGE
pi (mean)	1.76 × 10−3	3.88 × 10−3	2.71 × 10−3	4.38 × 10−3	3.00 × 10−3	9.48 × 10−4	3.04 × 10−4	1.07 × 10−3
pi (SD)	1.37 × 10−4	4.75 × 10−4	7.43 × 10−5	1.79 × 10−4	7.56 × 10−5	2.59 × 10−4	3.33 × 10−4	9.47 × 10−5
sig2_beta (mean)	6.31 × 10−5	2.45 × 10−5	3.37 × 10−5	7.43 × 10−6	6.13 × 10−5	6.15 × 10−5	1.11 × 10−4	2.57 × 10−4
sig2_beta (SD)	4.59 × 10−6	2.98 × 10−6	8.52 × 10−7	2.65 × 10−7	1.43 × 10−6	1.58 × 10−5	3.35 × 10−5	1.89 × 10−5
sig2_zero (mean)	1.09 × 100	1.02 × 100	1.12 × 100	1.05 × 100	1.22 × 100	1.19 × 100	1.17 × 100	1.13 × 100
sig2_zero (SD)	2.98 × 10−3	5.89 × 10−4	3.01 × 10−3	5.95 × 10−4	4.36 × 10−3	1.57 × 10−3	9.32 × 10−4	1.64 × 10−3
h2 (mean)	2.29 × 10−1	1.95 × 10−1	1.89 × 10−1	6.74 × 10−2	3.82 × 10−1	1.13 × 10−1	5.23 × 10−2	5.64 × 10−1
h2 (SD)	3.37 × 10−3	4.20 × 10−3	2.12 × 10−3	1.14 × 10−3	4.14 × 10−3	5.94 × 10−3	4.63 × 10−3	2.01 × 10−2
nc@p9 (mean)	5.60 × 103	1.24 × 104	8.60 × 103	1.40 × 104	9.60 × 103	3.02 × 103	9.69 × 102	3.40 × 103
nc@p9 (SD)	4.00 × 102	1.52 × 103	2.00 × 102	5.71 × 102	2.00 × 102	8.27 × 102	1.06 × 103	3.02 × 102
AIC	3.08 × 101	1.69 × 100	1.68 × 102	1.97 × 101	4.10 × 102	3.34 × 100	1.72 × 100	2.42 × 101

BIP = bipolar disorder; DEP = depression; EP = all epilepsy; FEP = focal epilepsy; h2 = heritability; nc@p9 = number of causal variants with strongest effects required to explain 90% variance at genome-wide significance; pi = polygenicity; SCZ = schizophrenia; sig2_beta = discoverability.