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. 2023 Jul 2;15(7):e41287. doi: 10.7759/cureus.41287

Table 5. The effect of cardiac protective agents on cardiac toxicity.

Variable Subvariable Total (n=78) N (%) Outcome cardiac toxicity Univariate analysis P-value
No n (%) 66(84.6) Yes n (%) 12(15.4) OR (95 % CI)
Use of cardio-protective drugs No 62(79.5) 54(87.1) 8(12.9) 0.44 (0.11 to 1.72) 0.240
Yes 16(20.5) 12(75.0) 4(25.0) Reference group
Beta-blocker No 68(87.2) 59(86.8) 9(13.2) 0.35 (0.07 to 1.63) 0.184
Yes 10(12.8) 7(70.0) 3(30.0) Reference group
ACE inhibitors No 63(80.8) 55(87.3) 8(12.7) 0.40 (0.10 to 1.56) 0.188
Yes 15(19.2) 11(73.3) 4(26.7) Reference group
Statins No 64(82.1) 57(89.1) 7(10.9) 0.22 (0.05 to 0.84) 0.028
Yes 14(17.9) 9(64.3) 5(35.7) Reference group
Antiplatelets No 71(91.0) 62(87.3) 9(12.7) 0.19 (0.03 to 1.01) 0.051
Yes 7(9.0) 4(57.1) 3(42.9) Reference group