Table 1.

Key questions for domains of percutaneous endoscopic gastrostomy

Area	Key question
Indications	KQ1. What is the indication for PEG?
Periprocedural use of prophylactic antibiotics	KQ 2. Should prophylactic antibiotics be administered to patients undergoing PEG using the pull or the push method?
Timing of initiating enteral nutrition	KQ 3. Should enteral feeding be started early after the PEG tube placement?
PEG technique	KQ 4. Should the push or pull method be used for patients undergoing PEG for the first time?
	KQ 4-1. Should the push or pull method be used in patients without esophageal cancer or head and neck cancer who are undergoing PEG for the first time?
	KQ 4-2. Should the push or pull method be used in patients with esophageal cancer or head and neck cancer who are undergoing PEG for the first time?
Complications	KQ 5. Should the PEG tube be removed in patients with persistent peristomal leakage?
	KQ 6. Should the PEG tube be replaced in cases of tubebreakage, occlusion, dislodgement, or degradation?
	KQ 7. Does loosening the external fixation device and adjusting the PEG tube help prevent BBS?
	KQ 8. Is endoscopic PEG tube removal effective in patients with BBS?
Feeding tube change and removal	KQ 9. When should the PEG tube be replaced in patients requiring chronic enteral nutrition?
	KQ 10. Is the cut-and-push technique appropriate for the removal of internal bolster-type PEG tubes?

KQ, key question; PEG, percutaneous endoscopic gastrostomy; BBS, buried bumper syndrome.