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. 2023 Jul 3;55(7):1413–1423. doi: 10.1038/s12276-023-01023-y

Fig. 7. DCN ameliorates mechanical stress-induced LFH in vivo.

Fig. 7

A Representative images of H&E- and EVG-stained LF tissues from rats in each group. Scale bar: 400 µm. B–E Quantitative analysis of the LF thickness, LF area, percentage of collagen fibers and elastic fibers, and LF fibrosis score in H&E- and EVG-stained sections (n = 10 rats in each group). F, G Representative images of immunohistochemical staining for collagen I and fibronectin in rat LF tissues under different interventions after 8 weeks. Scale bar: 400 µm (lower power lens); 200 µm (high power lens). H ELISAs of PINP and PIIINP levels in LF tissues from rats (n = 10 rats in each group). I ELISAs of PINP and PIIINP levels in serum samples from rats (n = 10 rats in each group). Data are presented as the means ± SDs. ns, no significance; *p < 0.05; **p < 0.01; ***p < 0.001.