Table 1.
The regulatory role of noncoding RNAs in cancer cells.
| Noncoding RNAs | Roles in cancer | Cancer | Reference | |
|---|---|---|---|---|
| MiRNA | MiR-431-5p | Inhibits tumor progression | PDAC | 108 |
| MiR-601 | Promotes cell proliferation by inhibiting the expression of TINP1 | GBM | 109 | |
| MiR-30d | Targets the transcription factor RUNX1 and inhibits the transcriptional activation of the RUNX1-induced Warburg effect | PDAC | 113 | |
| MiR-21-3p | Promotes cell growth and metastasis | Liver cancer | 114 | |
| MiR-378a | Inhibits PCa cell proliferation | Prostate cancer | 115 | |
| MiR-612 | Suppresses HCC cell invasion and migration | HCC | 116 | |
| MiR-4646-5p | Promotes metastasis | GC | 117 | |
| LncRNA | LncRNA H19 | Promotes the growth of oral tumors | Oral cancer | 119 |
| LncRNA ENO1-IT1 | Promotes glycolysis and tumorigenesis | CRC | 120 | |
| LncRNA NRCP | Promotes cancer cell growth | Ovarian cancer | 121 | |
| LINC00842 | Leads to a metabolic switch from mitochondrial oxidative catabolic processes to fatty acid synthesis, enhancing the malignant phenotype of PDAC cells | PDAC | 122 | |
| LncRNA ropm | Regulates the properties of breast cancer stem cells (BCSCs) by mediating lipid metabolism | Breast cancer | 123 | |
| Promotes the survival of glucose-deficient hepatoma cells by activating the serine synthesis pathway | HHC | 124 | ||
| LINC00467 | Promotes cell proliferation | CRC | 125 | |
| Lnc-NA | Regulates the expression of the nuclear receptor NR4A1 and then increases caspase signaling pathway activation, promoting apoptosis in endometrial cell lines | EC | 126 | |
| CircRNA | CircRPN2 | Increases the expression of FOXO1 to suppress glucose metabolism and tumor progression | HCC | 130 |
| CircMAT2B | Promotes glycolysis through the activation of circMAT2B/miR-338-3p/PKM2 axis to promote HCC progression under hypoxic conditions | HCC | 131 | |
| CircEZH2 | Promotes tumorigenesis and metastasis by sponging miR-217-5p and establishing a new feedback loop consisting of FUS/circEZH2/KLF5 | Breast cancer | 132 | |
| CircECE1 | Interacts with c-Myc to prevent POZ-mediated c-Myc ubiquitination and degradation | OS | 133 | |
| CircErbin | Promotes angiogenesis by increasing the expression of HIF-1α | CRC | 135 | |
| CircRNF13 | Inhibits proliferation and metastasis | NPC | 136 | |
| CircFNDC3B | Inhibits tumor progression by encoding the protein CircFNDC3B-218aa | Colon cancer | 138 |