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. 2023 Jul 3;55(7):1371–1379. doi: 10.1038/s12276-023-01028-7

Fig. 2. The role of the Kyn pathway in immune regulation.

Fig. 2

a The IDO1-AHR axis in the induction of infectious tolerance. b Suppression of IL6 expression by the IDO1-AHR axis in lung epithelial cells (ECs). c Cooperation of TGF-β1 and AHR in the transdifferentiation of Th17 cells into IL-10-producing Tr1 and Foxp3+ Treg cells. d The KynA-GPR35 axis in anti-inflammation and energy metabolism.