Figure 5.

SO-spindle coupling is the top sleep predictor of next-day glucose homeostasis

(A) Top sleep predictors of lower next-day fasting glucose, ranked in descending order of significance (negative log10 p value).

(B) Top sleep predictors of lower next-day insulin resistance (HOMA-IR) ranked in descending order. The proportion of SOs with significant coupling was the best sleep predictor of both fasting glucose and insulin resistance. Unadjusted two-tailed p values were obtained by fitting, for each sleep predictor separately, a multilevel regression model adjusted for age, gender, BMI, race/ethnicity, hypertension, and family identification. A total of 47 sleep parameters were included in the rank analysis. NREM refers to N2 + N3 sleep (N1 excluded). A full description of these parameters is provided in Tables S9 and S10.