TABLE 2.
Baseline Characteristics and Comorbidities by Weight Change Status for Objective 1 and Objective 2
| Variable | Total Sample | WG Cohort | No-Weight-Change Cohort | ≥ 3%-≤ 5% WL Cohort | ≥ 5%-≤ 10% WL Cohort | ≥ 10%-≤ 20% WL Cohort |
|---|---|---|---|---|---|---|
| Objective 1 | ||||||
| Sample size, n (%) | 20,488 (100) | 5,072 (24.8) | 11,588 (56.6) | 1,683 (8.2) | 1,576 (7.7) | 569 (2.8) |
| Age, years, mean (SD)a | 47.9 (9.9) | 46.2 (10.5) | 48.6 (9.5) | 48.7 (9.6) | 47.9 (10.4) | 46.3 (11.2) |
| Female, %a | 53.7 | 59.3 | 50.7 | 51.7 | 55.8 | 65.9 |
| Index BMI, mean (SD)a | 35.3 (5.4) | 35.1 (5.0) | 35.3 (5.3) | 35.6 (5.6) | 35.9 (6.0) | 36.5 (6.4) |
| Elixhauser Comorbidity Index score, mean (SD)a | 0.9 (1.1) | 0.9 (1.2) | 0.8 (1.1) | 0.9 (1.1) | 1.0 (1.2) | 1.2 (1.5) |
| Obesity-related comorbidities, n (%) | ||||||
| Dyslipidemiaa | 8,745 (42.7) | 1,980 (39.0) | 5,078 (43.8) | 777 (46.2) | 685 (43.5) | 225 (39.5) |
| Type 2 diabetes mellitusa | 3,854 (18.8) | 766 (15.1) | 2,139 (18.5) | 444 (26.4) | 398 (25.3) | 107 (18.8) |
| Osteoarthritis (knee, hip) | 880 (4.3) | 204 (4.0) | 527 (4.5) | 62 (3.7) | 65 (4.1) | 22 (3.9) |
| Gastroesophageal reflux diseasea | 2,397 (11.7) | 595 (11.7) | 1,294 (11.2) | 236 (14.0) | 194 (12.3) | 78 (13.7) |
| Hypertensiona | 9,283 (45.3) | 2,201 (43.4) | 5,294 (45.7) | 841 (50.0) | 701 (44.5) | 246 (43.2) |
| Musculoskeletal paina | 7,482 (36.5) | 1,904 (37.5) | 4,112 (35.5) | 617 (36.7) | 605 (38.4) | 244 (42.9) |
| Objective 2 | ||||||
| Sample size, n (%) | 15,307 (100) | 2,201 (43.4) | 9,097 (59.4) | 1,113 (7.3) | 964 (6.3) | 275 (1.8) |
| Age, mean (SD)a | 48.1 (9.9) | 46.3 (10.4) | 48.6 (9.5) | 49.5 (9.2) | 49.0 (10.0) | 47.6 (11.0) |
| Index BMI, mean (SD) | 35.3 (5.3) | 35.1 (5.0) | 35.2 (5.2) | 35.6 (5.6) | 36.1 (6.1) | 36.5 (6.3) |
| Elixhauser Comorbidity Index score, mean (SD)a | 0.9 (1.1) | 0.9 (1.2) | 0.8 (1.1) | 0.9 (1.1) | 1.0 (1.3) | 1.4 (1.7) |
| Obesity-related comorbidities, n (%) | ||||||
| Dyslipidemiaa | 6,560 (42.9) | 1,514 (39.2) | 3,932 (43.2) | 541 (48.6) | 444 (46.1) | 129 (46.9) |
| Type 2 diabetes mellitusa | 2,824 (18.4) | 549 (14.2) | 1,591 (17.5) | 335 (30.1) | 285 (29.6) | 64 (23.3) |
| Osteoarthritis (knee, hip) | 657 (4.3) | 150 (3.9) | 407 (4.5) | 45 (4.0) | 41 (4.3) | 14 (5.1) |
| Gastroesophageal reflux diseasea | 1,763 (11.5) | 454 (11.8) | 998 (11.0) | 156 (14.0) | 116 (12.0) | 39 (14.2) |
| Hypertensiona | 6,970 (45.5) | 1,692 (43.9) | 4,120 (45.3) | 575 (51.7) | 454 (47.1) | 129 (46.9) |
| Musculoskeletal paina | 5,507 (36.0) | 1,445 (37.5) | 3,174 (34.9) | 407 (36.6) | 361 (37.4) | 120 (43.6) |
a Differences with P < 0.05 based on chi-square tests.
BMI = body mass index; SD = standard deviation, WG = weight gain; WL = weight loss.