Table 3.
Factors associated with left atrial enlargement (LAE).
| Odds ratio (95% CI) | p-value | |
|---|---|---|
| Multivariable analysis including VCAM-1 AUC | ||
| High VCAM-1 AUC | 9.13 (3.21–25.95) | <0.001 |
| Agea | 1.21 (0.83–1.77) | 0.31 |
| Male | 0.52 (0.19–1.42) | 0.20 |
| Hypertension | 2.43 (0.85–6.95) | 0.10 |
| NIHSS score | 1.06 (0.97–1.15) | 0.20 |
| Glucose level at admissionb | 1.18 (0.84–1.66) | 0.34 |
| Atrial fibrillation | 7.47 (2.37–23.60) | 0.001 |
| Tandem occlusion | 0.38 (0.11–1.28) | 0.12 |
| Multivariable analysis including sST2 AUC | ||
| High sST2 AUC | 3.40 (1.68–6.86) | 0.001 |
| Agea | 1.90 (1.46–2.48) | <0.001 |
| Male | 0.45 (0.22–0.92) | 0.03 |
| Hypertension | 2.46 (1.24–4.92) | 0.01 |
| Current smoking | 0.31 (0.14–0.71) | 0.01 |
| Glucose level at admissionb | 1.37 (1.07–1.75) | 0.01 |
| Atrial fibrillation | 14.07 (5.67–34.90) | <0.001 |
| Tandem occlusion | 0.44 (0.20–0.97) | 0.04 |
CI, confidence interval; VCAM-1, vascular cellular adhesion molecule-1; AUC, area under the curve; sST2, soluble form suppression of tumorigenicity 2.
Multivariable model including VCAM-1 AUC along with age, sex, hypertension, NIHSS score, glucose level on admission, atrial fibrillation, and tandem occlusion (current smoking not retained by the backward selection).
Multivariable model including sST2 AUC along with age, sex, hypertension, current smoking, glucose level on admission, atrial fibrillation, and tandem occlusion (NIHSS score not retained by the backward selection).
The bold values indicates a p value < 0.05.
a
Per 10-year increase.
b
Per a 1-mmol/L increase.