Fig. 3. Anticancer effects of SCFAs in several types of cancers.
SCFA-producing gut microbes and SCFAs, mainly butyrate, derived from the gut microbiota were closely associated with the suppression of cancer cell growth via their regulation of apoptosis, autophagy, metabolism, EMT process, the cell cycle, signaling pathways and onco-/tumor suppressor genes in several types of cancers.