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. 2022 Dec 20;7(4):100019. doi: 10.1016/j.rpth.2022.100019

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© 2022 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

The relative numbers of δ- and α-granules are comparable between control and filamin A (FLNA)-null platelets. (A, B) Representative transmission electron microscope micrographs of (A) control and (B) FLNA-null platelets. Bar = 2 μm. (C) The bar graph depicts the mean number of α-granules per squared micrometer of cell area in control (red bars) and FLNA-null (platelet-specific knockout, blue bars) platelets. Data are presented as mean ± SEM (not significant, based on the Student’s t-test) and represent the analysis of a minimum of 50 platelets. (D) The bar graph depicts the mean number of δ-granules per squared micrometer of cell area in control (red bars) and FLNA-null (platelet-specific knockout, blue bars) platelets. Data are presented as mean ± SEM (ns, not significant, based on the Student’s t-test) and represent the analysis of a minimum of 50 platelets. KO, knockout; ns, not significant.