Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jul 19;14:1208780. doi: 10.3389/fphar.2023.1208780

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Basso, Chen, Zhou, Mark, LaSala, Dorfman, Atalla, Chun, Viramontes, Chang, Leifer, McDonald and Cipolla.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

(A–C) Onset and (D–F) Recovery of NSP Activities in Bone Marrow of C57BL/6 Mice Administered Repeated Doses of Brensocatib. The dotted horizontal lines represent the average (black) ± 1 SD (red) for the vehicle control. Data are plotted as mean ± SD (n = 4 for all brensocatib treatment groups, except for onset NE day 10, recovery PR3 day 6, and recovery CatG day 8 where n = 3 after removal of an outlier determined by Grubb’s test; n = 20 for vehicle control, except onset PR3 and recovery CatG where n = 19 after removal of outlier determined by Grubb’s test). *, p < 0.05 vs. vehicle; **, p < 0.01 vs. vehicle; ***, p < 0.001 vs. vehicle; ****, p < 0.0001 vs. vehicle.