TABLE 3.

Statistical comparison of BID vs. QD percent change from vehicle at matched dosing levels in C57BL/6 and BALB/c mice. p-values derived from Sidak’s multiple comparison test.

		NE	PR3	CatG
C57BL/6	Low Dose Brensocatib	0.6557	0.7154	0.2379
	Mid Dose Brensocatib	0.3965	0.9964	0.7873
	High Dose Brensocatib	0.4200	0.4362	0.7433
BALB/c	Low Dose Brensocatib	0.4226	0.3244	>0.9999
	Mid Dose Brensocatib	0.9731	0.6802	0.9722
	High Dose Brensocatib	0.2940	0.4308	0.8336