Table 1.
Baseline Characteristics of Participants with Monocyte Count and ILA Assessments
| Characteristic | MESA |
AGES-Reykjavik |
COPDGene |
ECLIPSE |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall | No ILA | ILA | Overall | No ILA | ILA | Overall | No ILA | ILA | Overall | No ILA | ILA | |
| No. participants | 484 | 421 | 63 | 3,547 | 3,211 | 336 | 2,719 | 2,256 | 463 | 646 | 509 | 137 |
| Age, yr, mean (SD) | 64 (9) | 63 (9) | 68 (10) | 76 (5) | 76 (5) | 78 (6) | 65 (9) | 64 (8) | 69 (9) | 63 (7) | 62 (7) | 65 (7) |
| Female, % | 54 | 53 | 62 | 58 | 59 | 45 | 49 | 49 | 48 | 33 | 35 | 25 |
| Race/ethnicity, % | ||||||||||||
| Non-Hispanic White | 47 | 45 | 54 | 100 | 100 | 100 | 73 | 72 | 78 | 100 | 100 | 100 |
| Asian | 11 | 12 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| African American | 19 | 20 | 19 | 0 | 0 | 0 | 27 | 28 | 22 | 0 | 0 | 0 |
| Hispanic | 23 | 23 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Smoking status, % | ||||||||||||
| Never | 49 | 50 | 38 | 44 | 46 | 29 | 0 | 0 | 0 | 0 | 0 | 0 |
| Former | 42 | 41 | 48 | 44 | 43 | 55 | 64 | 64 | 65 | 61 | 61 | 59 |
| Current | 9 | 9 | 14 | 12 | 12 | 16 | 36 | 36 | 35 | 39 | 39 | 41 |
| Height, cm, mean (SD) | 166 (10) | 166 (10) | 165 (11) | 167 (9) | 167 (9) | 168 (10) | 170 (10) | 170 (9) | 169 (10) | 170 (9) | 169 (9) | 170 (9) |
| Weight, kg, mean (SD) | 79 (18) | 79 (18) | 78 (18) | 76 (15) | 76 (15) | 77 (16) | 84 (20) | 84 (20) | 85 (20) | 78 (19) | 78 (19) | 77 (18) |
| Body mass index, kg/m2, mean (SD) | 29 (6) | 29 (6) | 29 (6) | 27 (4) | 27 (4) | 27 (5) | 29 (6) | 29 (6) | 30 (6) | 27 (6) | 27 (6) | 27 (5) |
| Absolute white blood cell count, ×103 μl, median (IQR) | 5.5 (4.6–6.5) | 5.4 (4.5–6.4) | 5.6 (4.8–7.0) | 4.7 (4.8–6.8) | 5.7 (4.8–6.7) | 6.1 (5.1–7.2) | 6.8 (5.7–8.3) | 6.8 (5.6–8.2) | 7.2 (6.1–8.6) | 7.4 (6.3–8.9) | 7.3 (6.2–8.6) | 8.3 (6.9–9.6) |
| Absolute monocyte count, ×103 μl, median (IQR) | 0.3 (0.2–0.4) | 0.3 (0.2–0.4) | 0.4 (0.3–0.5) | 0.5 (0.4–0.6) | 0.5 (0.4–0.6) | 0.6 (0.5–0.7) | 0.5 (0.4–0.7) | 0.5 (0.4–0.7) | 0.6 (0.5–0.7) | 0.5 (0.3–0.6) | 0.5 (0.3–0.6) | 0.5 (0.4–0.6) |
Definition of abbreviations: AGES-Reykjavik = Age, Gene/Environment Susceptibility-Reykjavik; COPD = chronic obstructive pulmonary disease; COPDGene = Genetic Epidemiology of COPD; ECLIPSE = Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points; ILA = interstitial lung abnormalities; IQR = interquartile range; MESA = Multi-Ethnic Study of Atherosclerosis.