Table 1.
Characteristic | British Columbia (n=11 942) | Scotland (n=7691) | England (n=2157) | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Pre-cirrhosis (n=10 083) | Cirrhosis (n=1013) | ESLD (n=846) | Pre-cirrhosis (n=5715) | Cirrhosis (n=1662) | ESLD (n=314) | Cirrhosis (n=1390) | ESLD (n=767) | |||
Year of SVR (median) | 2018 | 2016 | 2016 | 2017 | 2016 | 2016 | 2016 | 2015 | ||
Age (years), mean (SD) | 56.1 (10.6) | 60.3 (7.8) | 60.3 (7.7) | 44.4 (9.8) | 50.6 (8.9) | 52.5 (9.5) | 55.7 (9.4) | 57.1 (8.5) | ||
Sex | ||||||||||
Male | 6556 (65) | 703 (69) | 549 (65) | 4095 (72) | 1247 (75) | 213 (68) | 1028 (74) | 570 (74) | ||
Female | 3527 (35) | 310 (31) | 297 (35) | 1620 (28) | 415 (25) | 101 (32) | 362 (26) | 197 (26) | ||
Hospital admission for alcohol misuse | ||||||||||
No | 8664 (86) | 797 (79) | 520 (61) | 4377 (77) | 1143 (69) | 141 (45) | 1098 (79) | 410 (53) | ||
Yes (not recent) | 892 (9) | 99 (10) | 111 (13) | 837 (15) | 234 (14) | 46 (15) | 121 (9) | 104 (14) | ||
Yes (recent) | 527 (5) | 117 (12) | 215 (25) | 501 (9) | 285 (17) | 127 (40) | 171 (12) | 253 (33) | ||
Hospital admission for substance misuse | ||||||||||
No | 7437 (74) | 819 (81) | 632 (75) | 3009 (53) | 934 (56) | 176 (56) | 941 (68) | 419 (55) | ||
Yes (not recent) | 1418 (14) | 115 (11) | 93 (11) | 1432 (25) | 394 (24) | 61 (19) | 141 (10) | 71 (9) | ||
Yes (recent) | 1228 (12) | 79 (8) | 121 (14) | 1274 (22) | 334 (20) | 77 (25) | 308 (22) | 277 (36) | ||
Charlson comorbidity index | ||||||||||
0 | 8667 (86) | 825 (81) | 457 (54) | 5219 (91) | 1448 (87) | 205 (65) | 1017 (80) | 387 (51) | ||
1 | 629 (6) | 69 (7) | 101 (12) | 329 (6) | 138 (8) | 37 (12) | 200 (14) | 136 (18) | ||
2 | 410 (4) | 57 (6) | 183 (22) | 74 (1) | 46 (3) | 54 (17) | 54 (4) | 162 (21) | ||
≥3 | 377 (4) | 62 (6) | 105 (12) | 93 (2) | 30 (2) | 18 (6) | 29 (2) | 82 (11) |
Each cell provides the number of participants (corresponding column percentage), unless indicated otherwise. All column percentages have been rounded to the nearest integer. All data relate to baseline time point (date of successful hepatitis C treatment). ESLD=end stage liver disease; SD=standard deviation; SVR=sustained viral response.