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. 2023 Jul 19;14:1234885. doi: 10.3389/fphar.2023.1234885

TABLE 5.

Top ten most cited articles related to VRAC research.

Rank Title First author Journal Year Citations (n)
1 Identification of LRRC8 Heteromers as an Essential Component of the Volume-Regulated Anion Channel VRAC Felizia K Voss Science 2014 389
2 SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel Zhaozhu Qiu Cell 2014 366
3 Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models Michael J D Daniels Nature communications 2016 263
4 The rediscovery of platinum-based cancer therapy Sven Rottenberg Nature reviews cancer 2021 239
5 VRACs and other ion channels and transporters in the regulation of cell volume and beyond Thomas J Jentsch Nature review molecular cell biology 2016 177
6 Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs Rosa Planells-Cases EMBO Journal 2015 166
7 LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength Ruhma Syeda Cell 2016 150
8 VRACs and other ion channels and transporters in the regulation of cell volume and beyond Jonathan M Beckel Glia 2014 124
9 Structure of a volume-regulated anion channel of the LRRC8 family Dawid Deneka Nature 2018 107
10 ATP Release Channels Akiyuki Taruno International journal of molecular sciences 2018 105