Table 1.
Demographics with effect on ADT free survival at 5 years – Univariate analysis
| N = 1031 | %Risk ADT Free | N1 | HR2 | 95% CI2 | p-value | ||
|---|---|---|---|---|---|---|---|
| Age | 103 | 0.6 | |||||
| < 60 | 28 (27%) | 45% (29%, 69%) | — | — | |||
| 60–69 | 47 (46%) | 56% (43%, 73%) | 0.8 | 0.42, 1.53 | |||
| 70+ | 28 (27%) | 64% (47%, 87%) | 0.68 | 0.32, 1.46 | |||
| Treatment | 103 | 0.2 | |||||
| RP + Adj RT | 8 (7.8%) | — (—, —) | — | — | |||
| Brachy | 3 (2.9%) | — (—, —) | 0.69 | 0.14, 3.44 | |||
| RP | 35 (34%) | 52% (38%, 72%) | 0.48 | 0.19, 1.22 | |||
| RT alone | 13 (13%) | 38% (17%, 85%) | 0.52 | 0.17, 1.56 | |||
| RP + Salvage RT | 44 (43%) | 70% (57%, 85%) | 0.3 | 0.12, 0.76 | |||
| Gleason | 97 | 0.4 | |||||
| 3 + 4 | 29 (30%) | 69% (54%, 88%) | — | — | |||
| 4 + 3 | 30 (31%) | 60% (45%, 80%) | 1.41 | 0.66, 3.01 | |||
| 8+ | 38 (39%) | 43% (29%, 65%) | 1.59 | 0.78, 3.28 | |||
| Unknown | 6 | ||||||
| Nodes | 103 | 0.6 | |||||
| 1 | 80 (78%) | 58% (48%, 71%) | — | — | |||
| 2 | 19 (18%) | 50% (31%, 80%) | 1.06 | 0.51, 2.18 | |||
| 3 | 4 (3.9%) | 25% (4.6%, 100%) | 1.87 | 0.58, 6.07 | |||
| Doubling_time | 96 | 0.5 | |||||
| < 6m | 37 (39%) | 50% (36%, 70%) | — | — | |||
| 6m+ | 59 (61%) | 62% (50%, 77%) | 0.82 | 0.46, 1.49 | |||
| Unknown | 7 | ||||||
| SiteOfMets | 103 | 0.9 | |||||
| bone | 35 (34%) | 51% (36%, 72%) | — | — | |||
| mixed | 4 (3.9%) | 50% (19%, 100%) | 0.94 | 0.22, 4.06 | |||
| node (other) | 8 (7.8%) | 38% (15%, 92%) | 1.05 | 0.39, 2.84 | |||
| node (pelvic) | 56 (54%) | 61% (49%, 76%) | 0.79 | 0.44, 1.45 | |||
| SUVmax_group | 93 | 0.4 | |||||
| < 6.9 | 46 (49%) | 58% (44%, 75%) | — | — | |||
| 6.9+ | 47 (51%) | 57% (44%, 73%) | 1.31 | 0.73, 2.36 | |||
| Unknown | 10 | ||||||
| YearsSinceDx | 103 | 0.3 | |||||
| < 5 | 49 (48%) | — | — | ||||
| 5+ | 54 (52%) | 0.76 | 0.44, 1.31 | ||||
| PSA @ SBRT | 1.1 (0.5, 3.5) | 103 | 1.03 | 0.97, 1.09 | 0.4 | ||
1 n (%); Median (IQR)
2 HR = Hazard Ratio, CI = Confidence Interval