Table 3.
Cellular Immune Response in 8 Patients
| Parameter | Response, Median (IQR) | Patients, No. (%) | P Value | |||
|---|---|---|---|---|---|---|
| After 2 Doses | After 3 Doses | Change | Decreased Response | Increased Response | ||
| TNF-α–activated cells/1 × 106 CD4+ T cells | 645 (194–1965) | 645 (313–1383) | −242 (−1057 to–786) |
5 (63) | 3 (37) | .67 |
| IFN-γ–activated cells/1 × 106 CD4+ T cells | 384 (59–930) |
377 (230–777) |
−159 (−447 to 609) |
5 (63) | 3 (37) |
.78 |
| CD4+ T-cell count, cells/μL | 675 (568–922) |
764 (650–961) |
72 (−90 to 105) |
3 (37) | 5 (637) | .48 |
Abbreviations: IFN, interferon; IQR, interquartile range; TNF, tumor necrosis factor.