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. Author manuscript; available in PMC: 2024 Jul 1.
Published in final edited form as: Mutat Res Genet Toxicol Environ Mutagen. 2023 May 20;889:503649. doi: 10.1016/j.mrgentox.2023.503649

Figure 4.

Figure 4.

Mutation frequency in the 20 target sites of the Duplex Sequencing human mutagenicity panel measured in TK6 cells exposed to ENU at HC (left) and Inotiv-RTP (right). The mutation frequency at 48, 72, and 96 h were averaged (n=2 at each time point; n=6 in total). The target sites are listed on the Y-axis. Black indicates genic sites, blue indicates intergenic sites, and red indicates targets that include both genic and intergenic sequences. The target sites are ordered according to mutation frequency in HC samples at 100 μM from the lowest (top) to highest (bottom). Error bars represent standard error.