Table 1.
Baseline and clinical characteristics of patients with and without fever within 24 h after hematoma evacuation.
| Non-fever group (n = 89) | Fever group (n = 219) | p value | |
|---|---|---|---|
| Age, y, median (IQR) (y) | 55 (50–64) | 51 (43–60) | 0.005 |
| Female sex, n (%) | 35 (39.3) | 56 (25.6) | 0.016 |
| GCS at admission, median (IQR) | 8 (6–11) | 7 (6–10) | 0.083 |
| Systolic blood pressure at admission, median (IQR), (mm Hg) | 175 (158–189) | 177 (154–198) | 0.419 |
| Diastolic blood pressure at admission, median (IQR), (mm Hg) | 95 (86–109) | 100 (85–112) | 0.114 |
| Heart rate at admission, median (IQR) | 78 (70–90) | 84 (75–90) | 0.174 |
| Hypertension | 70 (78.7) | 162 (74.0) | 0.388 |
| Laboratory tests, median (IQR) | |||
| WBC × 109/L | 8.13 (6.19–10.29) | 8.80 (6.83–10.82) | 0.007 |
| Serum glucose, mmol/L | 6.93 (6.30–8.11) | 8.00 (6.75–9.90) | 0.069 |
| Hematoma profiles | |||
| Hematoma location, n (%) | 0.247 | ||
| Basal ganglia | 55 (61.8) | 139 (63.5) | |
| Lobe | 26 (29.2) | 62 (28.2) | |
| Epencephalon | 4 (4.5) | 14 (6.4) | |
| Thalamus | 2 (2.2) | 4 (1.8) | |
| Brainstem | 2 (2.2) | 0 (0) | |
| Intraventricular hemorrhage, n (%) | 41 (46.1) | 116 (53.0) | 0.272 |
| Volume of hematoma, median (IQR) | 44.38 (26.08–62.91) | 47.63 (28.94–70.68) | 0.651 |
| Body temperature profiles, median (IQR) | |||
| Body temperature at admission, (°C) | 36.5 (36.5–36.7) | 36.5 (36.5–36.7) | 0.516 |
| Maximum temperature within 24 h, (°C) | 37.2 (36.9–37.4) | 38.5 (38.0–39.0) | <0.001 |
| Minimum temperature within 24 h, (°C) | 36.2 (36.0–36.4) | 36.9 (36.5–37.3) | <0.001 |
| Fever burden, (°C × h) | 0.00 (0.00–0.00) | 7.00 (2.00–16.60) | <0.001 |
| Clinical outcomes | |||
| END, n (%) | 19 (21.3) | 63 (28.8) | 0.182 |
| 3-month mRS score, median (IQR) | 2 (2–5) | 3 (2–5) | 0.551 |
| 3-month poor functional outcome (mRS score > 2), n (%) | 44 (49.4) | 168 (54.5) | 0.251 |
p value < 0.05 was shown in bold. END, early neurological deterioration; GCS, Glasgow coma score; ICH, intracerebral hemorrhage; IQR, interquartile range; mRS, modified Rankin Scale; WBC, white blood cell count.