Table 3.

Statistical models of multivariable logistic regression investigating the association between the presence of causative mutation and development of atherosclerotic cardiovascular disease adjusted on confounders.

Model 1
	OR	95% CI	p-Value
Sex	1.823	(1.974–3.413)	0.061
Age	1.034	(1.009–1.060)	0.008
Mean LDL-c	2.658	(1.495–4.729)	0.001
Mean HDL-c	0.132	(0.016–1.073)	0.058
Model 2
	OR	95% CI	p-Value
Sex	1.880	(1.000–3.532)	0.050
Age	1.040	(1.014–1.067)	0.003
Causative mutation	1.713	(0.902–3.256)	0.100
Mean LDL-c	2.336	(1.298–4.205)	0.005
Mean HDL-c	0.148	(0.018–1.223)	0.076
Model 3
	OR	95% CI	p-Value
Sex	2.003	(1.076–3.728)	0.028
Age	1.044	(1.018–1.070)	0.001
Causative mutation	2.149	(1.170–3.948)	0.014
Mean HDL-c	0.236	(0.033–1.697)	0.151

OR, odds ratio; CI, confidence interval; LDL-c, low-density lipoprotein cholesterol; HDL-c, high-density lipoprotein cholesterol.