Table 4.
No causative mutation (N = 167) | LDLR (N = 97) | Apo B (N = 22) | PCSK9/Apo E (N = 3) | p-Value | |
---|---|---|---|---|---|
Total cholesterol (mg/dl) | 287 ± 42 | 297 ± 68 | 309 ± 55 | 289 ± 77 | 0.551 |
LDL-c (mg/dl) | 203 ± 37 | 225 ± 61 | 231 ± 52 | 218 ± 51 | 0.014 |
HDL-c (mg/dl) | 63 ± 30 | 55 ± 14 | 63 ± 15 | 64 ± 14 | 0.017 |
Lpa (mg/dl) | 46 ± 52 | 42 ± 46 | 37 ± 38 | 36 ± 34 | 0.986 |
Apo A1 (mg/dl) | 159 ± 23 | 149 ± 26 | 159 ± 26 | 174 ± 41 | 0.033 |
Apo B (mg/dl) | 146 ± 29 | 153 ± 42 | 162 ± 30 | 194 ± 81 | 0.150 |
LDL-R, low-density lipoprotein cholesterol receptor; PCSK9, proprotein convertase subtilisin/kexin type-9; Apo, apolipoprotein; LDL-c, low-density lipoprotein cholesterol; HDL-c, high-density lipoprotein cholesterol; Lpa, lipoprotein a.