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| Comp. | Ames prediction | Rat-male-FDA | Carcinogenic potency TD50 (mouse)a | Rat oral LD50b | Rat chronic LOAELb | Skin irritancy | Ocular irritancy |
|---|---|---|---|---|---|---|---|
| 15a | Non-mutagen | Non-carcinogen | 23.973 | 1.785 | 0.046 | Non-irritant | Mild |
| 15b | 18.268 | 1.580 | 0.108 | ||||
| 16 | 24.482 | 1.305 | 0.046 | ||||
| 17 | 27.036 | 0.768 | 0.062 | ||||
| Sorafenib | 19.236 | 0.823 | 0.005 |
Unit: mg kg−1 body weight per day.
Unit: g kg−1 body weight.
