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The geometric mean (GM) MIC and MIC range are presented for a wild-type (WT) strain and heterologous strains expressing either the class 2 DHODH from A. fumigatus (AF) or the class 1A DHODH from S. cerevisiae (SC), T. cruzi (TC), L. kluyveri (LK1A), M. circinelloides (MC) and R. arrhizus (RA).
| ura1Δ + | |||||||
|---|---|---|---|---|---|---|---|
| WT | AF | SC | TC | LK1A | MC | RA | |
| GM (mg/L) | >8 | 0.125 | >8 | >8 | >8 | >8 | >8 |
| Range (mg/L) | >8 | 0.125 | >8 | >8 | >8 | >8 | >8 |
