Fig 4. Main results of the hypothesis-free (GWAS) approach comparing commensal and BSI isolates using the portal of entry covariable.
A) Heritability estimates for the commensal phenotype. B) wg-GWAS model performance within each phylogroup. F1-score representation for the naive analysis (blue dots), with covariates (yellow dots), and the one expected by chance (grey dots). Numbers within parentheses below each phylogroup indicate the sample size. C) Virulence associated genes enrichment analysis for the different functional categories. The significance threshold is represented over the dotted line (Fisher’s exact test, p<0.05). PE: portal of entry.