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. 2022 Oct 5;31(7):452–458. doi: 10.1097/PAI.0000000000001071

TABLE 1.

NordiQC Scoring Criteria

Score Scoring Criteria Scoring Status
Optimal The staining is considered perfect or close to perfect in all of the included tissues. Sufficient: passed
Good The staining is considered fully acceptable in all of the included tissues. However, the protocol may be optimized to improve the proportion and/or staining intensity of cells demonstrated and/or optimize the technical quality as signal-to-noise ratio, morphology, etc. Sufficient: passed
Borderline The staining is considered insufficient, because of a generally too weak staining reaction, a false-negative/false-positive result in one of the included tissues and/or inferior technical quality. The protocol should be optimized. Insufficient: failed
Poor The staining is considered insufficient, because of a false-negative/false-positive result in 2* or more of the included tissues and/or inferior technical quality.
The protocol should be optimized.
Insufficient: failed
*

For type 2 IHC assays, 1 false-negative/false-positive result can be scored as poor.