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. 2023 Apr 4;38(5):217–230. doi: 10.1152/physiol.00004.2023

FIGURE 1.

FIGURE 1.

Heart failure with preserved ejection fraction-associated comorbidities increase circulating and activated, myocardium-infiltrating leukocytes Adipose tissue, in turn, contributes to circulating inflammatory signals. The resulting systemic and myocardial inflammation is characteristic of heart failure with preserved ejection fraction (HFpEF). HSC, hematopoietic stem cell.