Table 1.
Lomb–Scargle periodogram analysis of maternal blood pressure and heart rate circadian rhythms
| Saline |
ODN2395 |
|||||
|---|---|---|---|---|---|---|
| SBP | DBP | HR | SBP | DBP | HR | |
| n | 9 | 7 | ||||
| Acrophase (ZT) | ||||||
| GD14–16 | 20:15* | 21:00* | 16:55* | 20:12 | 20:28 | 21:44* |
| GD16–18 | 17:00* | 18:11* | 17:13* | 20:05* | 19:58* | 21:44* |
| GD18–20 | 17:00* | 17:00* | 17:14* | 18:44* | 17:00 | 17:00* |
| Amplitude, mmHg/(beats/min) | ||||||
| GD14–16 | 130.12* | 97.23* | 206.06* | 117.93 | 93.68 | 213.31* |
| GD16–18 | 129.48* | 95.36* | 205.83* | 119.61* | 93.79* | 211.93* |
| GD18–20 | 130.44* | 94.42* | 207.84* | 118.43* | 93.22 | 216.69* |
Acrophase in Zeitgeber time (0–12 = sleep phase, 07:00–19:00 h; 12–24 = wake phase, 19:00–07:00 h) and denotes the time of maximum value (peak). Amplitude expressed in native units [in mmHg for blood pressure and in beats/min for heart rate (HR)] and denotes the magnitude of the peak at given acrophase. *P < 0.05, significant periodicity detected. Boldface indicates no significant periodicity detected, representing a loss of circadian rhythmicity. GD, gestational days; SBP, systolic blood pressure; DBP, diastolic blood pressure.