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. 2023 Jul 5;325(3):E180–E191. doi: 10.1152/ajpendo.00084.2023

Figure 2.

Figure 2.

Upregulated UCP1, MCT1, and LDH in murine adipose tissue after burn. A: immunohistochemical staining for UCP1, MCT1, and LDH in inguinal WAT (iWAT) isolated from sham and burn mice at <1, 3, 7, and 14 days after injury. Gene expression of UCP1 (B), MCT1 (C), and Ldhb (D) in iWAT from sham and burn mice at <1, 3, 7, and 14 days after injury. Changes in plasma lactate (E), iWAT lactate (F), and iWAT [NADH/NAD+] (G) in sham (dotted line) and burn mice at <1, 3, 7, and 14 days after injury. Values are presented as means ± standard error. One-way ANOVA, Burn vs. sham *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001, n = 7/group. LDH, lactate dehydrogenase; MCT1, monocarboxylate transporter 1; PGC1α, peroxisome proliferator-activated receptor-γ coactivator 1-α; PPARγ, peroxisome proliferator-activated receptor γ; UCP1, uncoupling protein 1; WAT, white adipose tissue.