Figure 3.

Effect of daily l-lactate and Phloretin treatment on postburn mortality and body composition in vivo. A: Kaplan–Meier survival curves of control, vehicle-treated, l-lactate-treated, and Phloretin-treated burn mice over the course of 7 days. Changes in body weight (B), inguinal WAT (iWAT) expressed as a percentage of body weight (C), plasma lactate (D), and tissue lactate (E) in control, vehicle-treated, l-lactate-treated, and Phloretin-treated burn mice at 7 days after injury. Values are presented as means ± standard error. Log-rank test and one-way ANOVA, Burn vs. sham *P < 0.05; **P < 0.01; ***P < 0.001; ****P <0.0001, vehicle vs. treated burn #P < 0.05, ##P < 0.01, n = 7/group. WAT, white adipose tissue.