Table 4.
Diagnostic accuracy and relative risk of criterion hypohydration values in predicting urinary [IGFBP7·TIMP-2] > 0.3 (ng/mL)2/1,000
| Sensitivity | Specificity | Positive Predictive Value | Negative Predictive Value | Relative Risk | |
|---|---|---|---|---|---|
| Change in body mass loss ≥ 2% | 0.54 (0.35, 0.71) | 0.94 (0.74, 1.00) | 0.93 (0.70, 1.00) | 0.59 (0.41, 0.74) | 2.3 (1.5, 3.7) |
| Urine specific gravity > 1.020 au | 0.77 (0.58, 0.89) | 0.89 (0.67, 0.98) | 0.91 (0.72, 0.98) | 0.73 (0.52, 0.87) | 3.3 (1.8, 7.0) |
| Urine specific gravity ≥ 1.025 au | 0.67 (0.48, 0.81) | 0.94 (0.74, 0.99) | 0.94 (0.75, 0.99) | 0.65 (0.46, 0.81) | 2.7 (1.7, 4.9) |
| Urine osmolality ≥ 700 mosmol/kgH2O | 0.81 (0.62, 0.91) | 0.83 (0.61, 0.94) | 0.88 (0.69, 0.96) | 0.75 (0.53, 0.89) | 3.5 (1.8, 7.9) |
| Urine osmolality ≥ 800 mosmol/kgH2O | 0.73 (0.54, 0.86) | 0.89 (0.67, 0.98) | 0.90 (0.71, 0.98) | 0.70 (0.49, 0.84) | 3.0 (1.7, 5.9) |
| Urine osmolality ≥ 831 mosmol/kgH2O | 0.69 (0.50, 0.84) | 0.89 (0.67, 0.98) | 0.90 (0.70, 0.98) | 0.67 (0.47, 0.82) | 2.7 (1.6, 5.1) |
au, arbitrary units; [IGFBP7·TIMP-2], product of insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinase-2.