Table 1.
Socio-demographic and clinical characteristics of the sample
| Controls (n = 45) | OCD (n = 52) | P-value | |
|---|---|---|---|
| Age, years | 32.5 (8.7) | 30.2 (7.9) | 0.18 |
| Gender, % female | 40 | 44 | 0.68 |
| Handedness, % right | 96 | 85 | 0.08 |
| IQ-Full scalea | 112.7 (11.3) | 106.0 (12.5) | 0.007 |
| OBQ | 116.5 (47.1) | 196.8 (51.2) | <0.001 |
| OCI-R | 5.5 (7.1) | 33.2 (14.6) | <0.001 |
| HAM-A | 2.9 (3.1) | 19.5 (8.6) | <0.001 |
| HADS Anxiety; Depression | 4.8 (3.7); 2.2 (2.3) | 13.3 (4.7); 8.2 (4.8) | <0.001 |
| MADRS | 2.9 (3.5) | 19.5 (10.4) | <0.001 |
| Y-BOCS Total | 1.8 (3.0) | 25.3 (5.2) | <0.001 |
| Symptoms dimensions | Absent–Mild–Severe | ||
| ȃSexual/Religious | 100–0–0% | 31–39–30% | <0.00001 |
| ȃSymmetry/Ordering | 100–0–0% | 51–39–10% | <0.00001 |
| ȃHoarding | 100–0–0% | 61–31–8% | <0.00001 |
| ȃContamination/Cleaning | 98–2–0% | 12–16–72% | <0.00001 |
| ȃAggressive/Checking | 89–9–2% | 6–8–86% | <0.00001 |
Values are presented as mean (standard deviation) unless otherwise stated. P-values relate to Student’s t-test for continuous data and χ2 test for categorical data. Y-BOCS symptoms dimensions computed as in previously reported.4,11 HADS = Hospital Anxiety and Depression scale; HAM-A = Hamilton Anxiety Rating Scale; MADRS = Montgomery-Asberg Depression rating scale; OBS = Obsessional Beliefs Questionnaire; OCI-R = Obsessive Compulsive Inventory-Revised; Y-BOCS = Yale-Brown Obsessive Compulsive Scale.
Wechsler Adult Intelligence Scale (WAIS-IV).