Table 3.
Influence of source of exposure on associations of animal exposure with atopic dermatitis, asthma and allergic rhinoconjunctivitis
| Atopic dermatitis |
Asthma |
Allergic rhinoconjunctivitis |
|||||
|---|---|---|---|---|---|---|---|
| Minimally adjusteda HR (95% CI) | Adjustedb HR (95% CI) | Minimally adjusteda HR (95% CI) | Adjustedb HR (95% CI) | Minimally adjusteda HR (95% CI) | Adjustedb HR (95% CI) | ||
| Cat | No exposure | – | – | – | – | – | – |
| Domestic | 0.84 (0.73,0.97) | 0.92 (0.80,1.06) | 0.89 (0.83,0.95) | 0.95 (0.89,1.01) | 0.92 (0.89,0.96) | 0.97 (0.94,1.00) | |
| Otherc | NA | NA | 1.23 (0.71,2.12) | 1.36 (0.76,2.43) | 0.90 (0.65,1.26) | 1.20 (0.84,1.70) | |
| Dog | No exposure | – | – | – | – | – | – |
| Domestic | 0.77 (0.67,0.89) | 0.81 (0.69,0.94) | 0.86 (0.81,0.92) | 0.88 (0.82,0.95) | 0.91 (0.88,0.94) | 0.93 (0.90,0.97) | |
| Otherc | NA | NA | NA | NA | 0.40 (0.19,0.84) | 0.42 (0.19,0.92) | |
| Rabbit | No exposure | – | – | – | – | – | – |
| Domestic | 1.04 (0.79,1.37) | 1.16 (0.88,1.53) | 1.03 (0.91,1.17) | 1.09 (0.96,1.24) | 0.79 (0.73,0.85) | 0.88 (0.81,0.95) | |
| Otherc | NA | NA | 1.05 (0.50,2.23) | 1.28 (0.58,2.82) | 0.69 (0.42,1.14) | 0.90 (0.54,1.47) | |
| Rodent | No exposure | – | – | – | – | – | – |
| Domestic | 1.07 (0.75,1.54) | 1.13 (0.78,1.63) | 1.05 (0.89,1.24) | 1.06 (0.89,1.26) | 0.93 (0.84,1.02) | 1.00 (0.90,1.10) | |
| Otherc | NA | NA | 0.94 (0.39,2.26) | 0.96 (0.39,2.38) | 0.84 (0.51,1.41) | 1.04 (0.61,1.76) | |
| Birds | No exposure | – | – | – | – | – | – |
| Domestic | 0.86 (0.64,1.14) | 0.85 (0.64,1.13) | 1.19 (1.06,1.34) | 1.18 (1.05,1.32) | 0.97 (0.91,1.04) | 1.00 (0.93,1.07) | |
| Otherc | 0.78 (0.51,1.17) | 0.99 (0.64,1.54) | 0.88 (0.73,1.05) | 0.95 (0.78,1.16) | 0.72 (0.65,0.80) | 0.83 (0.74,0.93) | |
| Livestock | No exposure | – | – | – | – | – | – |
| Domestic and farm | 0.66 (0.50,0.87) | 0.78 (0.58,1.06) | 0.86 (0.77,0.97) | 1.01 (0.88,1.15) | 0.81 (0.76,0.87) | 0.95 (0.88,1.02) | |
| Otherd | NA | NA | 1.43 (0.81,2.52) | 1.52 (0.86,2.69) | 0.95 (0.64,1.40) | 1.02 (0.69,1.50) | |
HR, hazard ratio; NA, effect estimates not available due to risk of disclosure.
a
Adjusted for age (underlying time scale) and sex.
b
Additionally adjusted for maternal asthma, maternal inhalant allergy, paternal asthma, paternal allergy, maternal education, equivalized disposable household income, maternal age at birth, number of children living in the home, household crowding, smoking during pregnancy and living in Copenhagen, plus mutually adjusted for other animal exposures.
c
Farm- and occupation-related exposure.
d
Occupation-related exposure.