表3 不同ONT的急性缺血性卒中患者从静脉溶栓治疗中获益的最大梗死体积阈值
Table 3 Maximun infarct volume benefits from intravenous thrombolysis in acute ischemia stroke patients with different onset to needle time
|
起病至静脉溶栓时间(h) |
n |
基线梗死体积[ M( Q 1~ Q 3), mL] |
临床预后不良[ n(%)] |
受试者工作特征曲线下面积 |
95% CI |
100%特异度阈值(mL) |
|
＜1.5 |
41 |
21(5~61) |
14(34.1) |
0.687 |
0.521~0.852 |
148 |
|
1.5~＜2 |
46 |
28(9~57) |
17(37.0) |
0.663 |
0.499~0.827 |
93 |
|
2~＜2.5 |
64 |
16(1~47) |
22(34.4) |
0.783 |
0.663~0.903 |
132 |
|
2.5~＜3 |
88 |
8(1~41) |
39(44.3) |
0.785 |
0.684~0.886 |
87 |
|
3~＜3.5 |
63 |
5(1~38) |
27(42.9) |
0.726 |
0.598~0.853 |
100 |
|
3.5~＜4 |
79 |
12(2~41) |
36(45.6) |
0.623 |
0.496~0.750 |
118 |
|
4~＜4.5 |
88 |
11(1~42) |
41(46.6) |
0.815 |
0.725~0.906 |
152 |
|
4.5~＜5 |
30 |
27(12~67) |
18(60.0) |
0.766 |
0.596~0.936 |
69 |
|
5~＜5.5 |
25 |
20(3~57) |
10(40.0) |
0.800 |
0.623~0.977 |
72 |
|
5.5~＜6 h |
22 |
17(7~44) |
14(63.6) |
0.616 |
0.368~0.864 |
64 |
|
≥6 |
41 |
11(4~40) |
25(61.0) |
0.709 |
0.541~0.877 |
53 |