表1 aSAH重症患者甘露醇治疗后各时段颅内压、平均动脉压、脑灌注压、中心静脉压和血钠浓度和血浆渗透压变化
Table 1 The changes of intracranial pressure, mean arterial pressure, cerebral perfusion pressure, central venous pressure, blood sodium concentration and plasma osmotic pressure after treatment with 20% mannitol in patients with severe aneurysmal subarachnoid hemorrhage
|
( x ± s) | |||||||
|
组别 |
颅内压(mm Hg) |
平均动脉压(mm Hg) |
脑灌注压(mm Hg) |
中心静脉压(cm H 2O) |
血钠浓度(mmol/L) |
血浆渗透压(mOsm/L) |
|
|
用药前 |
22.3±4.1 |
98±7.1 |
75±9.7 |
9.1±2.2 |
140.5±9.1 |
295.5±11.3 |
|
|
用药后 |
30 min |
13.2±3.3 |
102±9.3 |
90±7.3 |
9.2±2.1 |
— |
— |
|
1 h |
14.9±3.5 |
99±9.1 |
84±8.3 |
9.4±2.3 |
138.3±8.9 |
316.6±14.1 |
|
|
2 h |
15.8±3.4 |
98±9.5 |
82±7.5 |
9.6±2.1 |
— |
— |
|
|
3 h |
16.5±2.3 |
97±9.3 |
80±7.8 |
9.3±2.0 |
136.1±9.3 |
301.5±13.0 |
|
|
4 h |
17.9±3.1 |
95±9.1 |
77±8.1 |
9.0±2.1 |
— |
— |
|
|
F值 |
39.02 |
1.59 |
17.53 |
0.23 |
4.95 |
5.89 |
|
|
P 值 |
< 0.01 |
> 0.05 |
< 0.01 |
> 0.05 |
< 0.05 |
< 0.05 |
—：未测