表2 aSAH重症患者高渗盐水治疗后各时段颅内压、平均动脉压、脑灌注压、中心静脉压和血钠浓度、血浆渗透压变化
Table 2 The changes of intracranial pressure, mean arterial pressure, cerebral perfusion pressure, central venous pressure, blood sodium concentration and plasma osmotic pressure after treatment with 3% hypertonic saline solution in patients with severe aneurysmal subarachnoid hemorrhage
|
( x ± s) | |||||||
|
组别 |
颅内压(mm Hg) |
平均动脉压(mm Hg) |
脑灌注压(mm Hg) |
中心静脉压(cm H 2O) |
血钠浓度(mmol/L) |
血浆渗透压(mOsm/L) |
|
|
用药前 |
22.9±4.3 |
96±7.9 |
76±6.9 |
9.3±2.1 |
138.1±8.3 |
289.4±10.3 |
|
|
用药后 |
30 min |
13.0±3.7 |
107±9.6 |
94±7.0 |
9.3±2.4 |
— |
— |
|
1 h |
13.5±3.3 |
104±9.0 |
90±8.1 |
9.6±2.1 |
149.3±9.8 |
329.6±15.8 |
|
|
2 h |
14.6±3.4 |
102±9.5 |
88±7.7 |
9.8±2.0 |
— |
— |
|
|
3 h |
15.3±2.9 |
100±9.4 |
85±7.3 |
10.1±1.8 |
143.5±8.1 |
310.6±12.1 |
|
|
4 h |
17.8±3.3 |
99±9.1 |
81±8.5 |
10.3±2.0 |
— |
— |
|
|
F值 |
59.13 |
1.52 |
19.64 |
0.31 |
5.56 |
6.38 |
|
|
P值 |
< 0.01 |
> 0.05 |
< 0.01 |
> 0.05 |
< 0.05 |
< 0.05 |
—：未测