Fig. 8. Cortical damage as a function of acoustic pressure and microbubble dosage.
a Evans blue microscopy image of sonication at 0.95 MPa with 100 µl/kg microbubble dose in Marmoset G. b H&E stained slice of interest from (a). Black boxes overlaying the H&E images show the location of the zoomed image below. c GBCA image of sonication at 0.95 MPa with 0.95 MPa with 200 µl/kg microbubble dose in Marmoset T. d H&E for (c). e Same as (a), using 1.17 MPa with 200 µl/kg microbubble dose in Marmoset NE. f H&E for (e). g Same as (a), Marmoset T: 1.17 MPa, 200 µl/kg microbubble dose. h H&E for (g). i Same as (a), Marmoset SK: 1.7 MPa, 400 µl/kg microbubble dose. j H&E for (h). k Same as (a), Marmoset E: 1.7 MPa, 400 µl/kg microbubble dose. l H&E for (k).