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. 2023 Aug 2;6:802. doi: 10.1038/s42003-023-05157-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Final reconstructed volumes of the full-length WzzE refined without and with the application of C4 and C8 symmetry. Top: view looking down from the top of the periplasmic domain. The application of C8 symmetry averages out the density for the alternating conformations of the L4 loops. Blue outline represents the four asymmetric units. b Cartoon representation of the octameric complex overlaid with the C4 symmetrized WzzE map (white).