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. 2023 May 23;33(8):604–616. doi: 10.1038/s41422-023-00808-0

Fig. 7. G protein coupling of dopamine receptors.

Fig. 7

a The structures of the D1R–Gs, D2R–Gi, D3R–Gi, D4R–Gi, and D5R–Gs complexes. b Comparison of the G protein conformations among the structures of D1R–Gs, D2R–Gi, D3R–Gi, D4R–Gi, and D5R–Gs complexes. c Structural comparison focused on the α5 helix of the Gα subunit bound to dopamine receptors. d Comparison of the G protein conformations among the structures of D1R–Gs and D5R–Gs complexes. e Comparison of the G protein conformations among the structures of D2R–Gi, D3R–Gi, and D4R–Gi complexes.