Fig. 1. The level of genomic 6mA in C. elegans is increased by pathogen infection.
a–d 6mA dot blotting (a, c) and quantification (b, d) of WT animals under each indicated treatment. n = 3. Bars indicate means + SD. Two-tailed t-test, *P < 0.05, **P < 0.01, ***P < 0.001. e LC-MS/MS analysis of gDNA 6mA level in WT animals fed on OP50, PA14, PAO1 or Rhodococcus. n = 4. Bars indicate means + SD. Two-tailed t-test, *P < 0.05, **P < 0.01, ***P < 0.001. f Slow-killing assay of WT animals fed on OP50, PA14, PAO1 or Rhodococcus. n = 100. Log-rank (Mantel–Cox) test, ****P < 0.0001.