Fig. 3. Circ235 promotes tumorigenesis in vivo.
A 1 × 107 T24 cells were injected hypodermically into mice, and typical photographs of tumors were obtained after 27 days. B Tumor volumes were recorded every 4 days from 7 days post-injection. C Tumor weights of mice in each group were recorded after dissection (n = 5 per group). D, E The progression of the subcutaneous tumor was tracked by an IVIS, and typical photographs of subcutaneous tumors were obtained. Total fluorescence intensity region of interest (ROI) counts was proceeded to detect the cellular activity of subcutaneous tumors (n = 3 per group). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.