Table 1.

CDH1 promoter methylation analysis.

	Methylation− (cases)	Methylation+ (cases)	P value
Age ≧ 65 years	57.7% (60/104)	42.3% (44/104)	0.054
Male	51.6% (33/64)	48.4% (31/64)
Female	54.4% (37/68)	45.6% (31/68)	0.862
BMI ≧ 25 kg/m2	48.6% (17/35)	51.4% (18/35)	0.559
DM	43.1% (28/65)	56.9% (37/65)	<0.05
Short‐DM	56.3% (18/32)	43.8% (14/32)	0.690
Long‐DM	30.3% (10/33)	69.7% (23/33)	<0.01
HbA1c ≧ 6.5%	42.2% (19/45)	57.8% (26/45)	0.098
Diet therapy	45.5% (10/22)	54.5% (12/22)	0.488
Metformin user	37.5% (3/8)	62.5% (5/8)	0.474
DPP4 inhibitor user	41.2% (14/34)	58.8% (20/34)	0.116
Insulin user	36.4% (4/11)	63.6% (7/11)	0.347
Smoker	46.4% (32/69)	53.6% (37/69)	0.120
E‐cadherin, low	39.0% (23/59)	61.0% (36/59)	<0.01