Table 1.
Patient clinical history, P2-Flow (TCD), stroke etiology and clinical scores.
| All n = 111 (%) |
No recurrence n = 98 (%) |
Recurrence n = 13 (%) |
p value | |
|---|---|---|---|---|
| Demographic data | 0.209 | |||
| Age, median years (IQR) | 66 (23.5) | 66 (23.7) | 65 (20.4) | 0.962 |
| Female, n (%) | 31 (27.9) | 26 (26.5) | 5 (38.5) | 0.511 |
| Medical history and risk factors, n (%) | ||||
| Previous stroke | 12 (10.8) | 9 (9.2) | 3 (23.1) | 0.148 |
| Previous TIA | 14 (12.6) | 7 (7.1) | 7 (53.8) | 0.001 |
| Hypertension | 77 (69.4) | 65 (66.3) | 12 (92.3) | 0.105 |
| Diabetes | 22 (19.8) | 18 (18.4) | 4 (30.8) | 0.458 |
| Dyslipidaemia | 66 (59.5) | 59 (60.2) | 7 (53.8) | 0.766 |
| Smoking | 37 (33.3) | 33 (33.7) | 4 (30.8) | 1.000 |
| Coronary heart disease | 15 (13.5) | 12 (12.2) | 1 (7.7) | 0.380 |
| Peripheral artery disease | 11 (9.9) | 8 (8.2) | 3 (23.1) | 0.119 |
| Pre-stroke medication, n (%) | ||||
| Antiplatelets | 47 (42.3) | 40 (40.8) | 7 (53.8) | 0.552 |
| Anticoagulants | 17 (15.3) | 11 (11.2) | 6 (46.2) | 0.005 |
| Statins | 31 (27.9) | 24 (24.5) | 7 (53.8) | 0.034 |
| TCD flow velocity, cm/s, median (IQR) | ||||
| Ipsilateral PCA-P2 PSV | 62 (26) | 60 (26) | 86 (41) | <0.001 |
| Ipsilateral PCA-P2 EDV | 25 (12) | 25 (10) | 42 (21) | <0.001 |
| Stroke etiology, n (%) | 0.209 | |||
| TOAST 1 large artery atherosclerosis | 48 (43.2) | 39 (39.8) | 9 (69.2) | |
| TOAST 2 cardiac | 20 (18) | 19 (19.4) | 1 (7.7) | |
| TOAST 3 lacunar | 0 | 0 | 0 | |
| TOAST 4 other determined | 25 (22.5) | 24 (24.5) | 1 (7.7) | |
| TOAST 5 undetermined | 9 (8.1) | 8 (8.2) | 1 (7.7) | |
| TOAST 5 more than one etiology | 9 (8.1) | 8 (8.2) | 1 (7.7) | |
| Clinical scores, median (IQR) | ||||
| NIHSS on admission | 4 (11) | 5 (12) | 1 (3) | 0.005 |
| Pre-stroke mRS | 0 (3) | 0 (3) | 1 (2) | 0.318 |
| mRS 3 months | 1 (3) | 1 (3) | 1 (1) | 0.706 |
Information on patient clinical history, P2-Flow (TCD), stroke etiology and clinical scores (NIHSS on admission, pre- stroke mRS and 3-months-mRS) of all 111 patients and patient groups (no recurrence/ recurrence). Data are expressed as number of patients (n) and percentages or median. p values were obtained according to Mann–Whitney U test, Pearson’s Chi-squared test and Fisher’s exact test, where appropriate. p values < 0.05 are shown in bold. TIA, transient ischaemic attack; PSV, peak systolic velocity; EDV, end diastolic velocity; PCA, posterior cerebral artery.