TABLE 1.

Pharmacokinetic data of rats.

Parameter	BBR-I-O	BBR-I-S	BBR-PPSG-S
AUC (0-t) ng/L*h	7654.13 ± 638.47	23,451.97 ± 7387.07	94,679.83 ± 7280.92
t1/2 h	19.4 ± 6.96	14.45 ± 0.52	215.87 ± 138.91
Tmax h	1.00	1.40 ± 1.48	0.70 ± 0.27
Cmax ng/L	1607.04 ± 221.91	5001.54 ± 1274.02	2425.81 ± 220.12