Table 4.

Inflammatory Criteria of Chronic Dextran Sulfate Sodium-Induced Colitis in This Study

Sub-criteria	Score
Inflammation	0: None to normal lymphoid aggregates
	1: Increased lymphoid aggregates
	2: Cryptitis (neutrophils within crypt epithelium)
	3: Crypt abscess (neutrophils accumulating within crypt lumen, sometimes with crypt rupture)
	4: Ulceration (loss of mucosal components and presence of granulation tissue)
Extent of leukocyte infiltration	0: None
	1: Infiltration confined to the mucosa
	2: Infiltration extending to the submucosa
	3: Transmural extension of infiltration
Severity of leukocyte infiltration	0: None
	1: Mild
	2: Moderate
	3: Severe
The extent of colonic infiltration	0: None
	1: Patchy (focal)
	2: Intermediate
	3: Diffuse (extensive)