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. 2023 May 22;122(13):2675–2685. doi: 10.1016/j.bpj.2023.05.021

Figure 6.

Figure 6

PIP2 effects CD44 structure in a phosphorylation-dependent manner. (a) Distance evolution of the phosphorylated CD44-CTDs with FERM in the bilayer of 80% POPC/20% POPS. (b) The representative binding mode of CD44-S325p and FERM in the 80% POPC/20% POPS membrane. (c) Distance evolution between the centers of mass of FERM and the lower lipid headgroups along the membrane normal in the membranes composed of 95% POPC/5% PIP2 (left) and 80% POPC/20% POPS (right). 10 replicas are analyzed and averaged by a bold line for each system. To see this figure in color, go online.