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. 2018 Dec;24(12):10.18553/jmcp.2018.24.12.1230. doi: 10.18553/jmcp.2018.24.12.1230
Brand Name Generic Name FDA Approval Indication Administration Exclusion Reason
Lucentis Ranibizumab 6/30/2006 Macular degeneration Intravitreal Part B
Soliris Eculizumab 3/16/2007 Paroxysmal nocturnal hemoglobinuria IV infusion Part B
Entereg Alvimopan 5/20/2008 Aids recovery of bowel resection surgery PO post-op Part A
Cleviprex Clevidipine 8/1/2008 Blood pressure control when oral therapy not feasible IV infusion Part B
Nplate Romiplostim 8/22/2008 Idiopathic (immune) thrombocytopenic purpura Subcutaneous Part B
Lusedra Fospropofol 12/12/2008 Sedation IV infusion Part B
Kalbitor Ecallantide 12/1/2009 Hereditary angioedema Subcutaneous Part B
Xiaflex Collagenase clostridium histolyticum 2/2/2010 Dupuytren’s disease Injection Part A/B
Asclera Polidocanol 3/30/2010 Varicose veins IV injection Part A/B
Krystexxa Pegloticase 9/14/2010 Hyperuricemia/gout IV infusion Part B
Adcetris Brentuximab vedotin 8/19/2011 Hodgkin lymphoma (third-line agent) IV infusion Part B
Eylea Aflibercept 11/18/2011 Macular degeneration Intravitreal Part B
Kyprolis Carfilzomib 7/20/2012 Multiple myeloma (third-line agent) IV infusion Part B
Jetrea Ocriplasmin 10/17/2012 Vitreomacular adhesion Intravitreal Part B

FDA = U.S. Food and Drug Administration; IV = intravenous; PO = per oral.