TABLE 3.
Baseline Characteristics of Patients in Statin Adherence Cohort (N = 949)
| Overall (N = 949) | Guideline (n = 588) | Historical (n = 361) | P Valuea | ||||
|---|---|---|---|---|---|---|---|
| n | % | n | % | n | % | ||
| Demographics | |||||||
| Age, mean [SD] | 59.8 | [7.0] | 58.4 | [6.9] | 62.2 | [6.6] | < 0.001 |
| Male | 742 | 78.2 | 467 | 79.4 | 275 | 76.2 | 0.274 |
| Clinical characteristics | |||||||
| Hyperlipidemia | 851 | 89.7 | 534 | 90.8 | 317 | 87.8 | 0.172 |
| Hypertension | 727 | 76.6 | 454 | 77.2 | 273 | 75.6 | 0.630 |
| Diabetes | 186 | 19.6 | 120 | 20.4 | 66 | 18.3 | 0.474 |
| Overweight | 8 | 0.8 | 5 | 0.9 | 3 | 0.8 | 1.000 |
| Obesity | 118 | 12.4 | 76 | 12.9 | 42 | 11.6 | 0.613 |
| Anxiety | 8 | 0.8 | 3 | 0.5 | 5 | 1.4 | 0.165 |
| Depression | 26 | 2.7 | 17 | 2.9 | 9 | 2.5 | 0.873 |
| Bipolar | 2 | 0.2 | 1 | 0.2 | 1 | 0.3 | 1.000 |
| Psychotic disorder | 2 | 0.2 | 1 | 0.2 | 1 | 0.3 | 1.000 |
| Pre-index statin intensity | |||||||
| Low-intensity statin | 17 | 1.8 | 11 | 1.9 | 6 | 1.7 | < 0.001 |
| Moderate-intensity statin | 553 | 58.3 | 296 | 50.3 | 257 | 71.2 | |
| High-intensity statin | 379 | 39.9 | 281 | 47.8 | 98 | 27.1 | |
| Pre-index statin copay, mean [SD] | $20.02 | [$25.19] | $17.80 | [$24.51] | $23.25 | [$25.81] | < 0.001 |
a Continuous variables compared between guideline and historical groups using t-tests, categorical variables compared using chi-square test, or Fisher’s exact tests as appropriate.
SD = standard deviation.