Overall (N = 1,526)		Guideline (n = 763)		Historical (n = 763)		P Valuea
	n	%	n	%	n	%
Demographics
Age, mean [SD]	59.5	[8.1]	60.5	[8.6]	58.6	[7.5]	< 0.001
Male	1,110	72.7	543	71.2	567	74.3	0.187
Clinical characteristics
Hyperlipidemia	1,232	80.7	610	79.9	622	81.5	0.454
Hypertension	1,124	73.7	560	73.4	564	73.9	0.860
Diabetes	260	17.0	130	17.0	130	17.0	1.000
Overweight	13	0.9	5	0.7	8	1.0	0.579
Obesity	196	12.8	77	10.1	119	15.6	0.002
Anxiety	19	1.2	11	1.4	8	1.0	0.646
Depression	42	2.8	22	2.9	20	2.6	0.877
Bipolar	8	0.5	7	0.9	1	0.1	0.077
Psychotic disorder	3	0.2	1	0.1	2	0.3	1.000
Pre-index antihyperlipidemic medication use
Antihyperlipidemic medication classes
None	370	24.2	185	24.2	185	24.2	1.000
Nonstatin medication	160	10.5	80	10.5	80	10.5
Low-intensity statin	20	1.3	10	1.3	10	1.3
Moderate-intensity statin	728	47.7	364	47.7	364	47.7
High-intensity statin	248	16.3	124	16.3	124	16.3
Antihyperlipidemic copay, mean [SD]b	$22	[$26]	$19	[$26]	$24	[$26]	< 0.001
Number of antihyperlipidemic fills, mean [SD]b	7.6	[5.3]	6.6	[4.3]	8.5	[6.1]	< 0.001

^a Continuous variables compared between guideline and historical groups using paired t-tests, and categorical variables compared using McNemar’s test or Maxwell-Stuart test as appropriate.

^b Among patients with at least 1 antihyperlipidemic fill.

SD = standard deviation.